Backblaze Computer Backup automatically backs up everything on your Mac to the cloud, with unlimited storage. Set it up once and it runs quietly in the background.

Key features:

Back up all user files and connected external drives, with no limits on file type or size.
Back up continuously and automatically as you work.
Encrypt files before they leave your Mac, with an optional private encryption key.
Restore through the app, the web or mobile, or order a USB drive of your data by mail.
Locate a lost or stolen computer.
Share individual files you have backed up.

Backblaze has a native Mac client with no Java. Personal backup costs $9 a month, $99 a year or $7.88 a month on a two-year plan, and a free trial needs no credit card. Mailed USB restore drives are refunded when returned within 30 days.